UC Associate Professor Laurie McKay is a sleep expert, specialising in children who are on the autism spectrum and typically don't naturally produce melatonin as efficiently as other children.
The study鈥檚 lead author听Associate Professor Laurie McLay听says the treatment, which mimics the body鈥檚 natural sleep hormone, can make a huge difference for families with children on the autism spectrum.
鈥淲e know that sleep problems are really common for children on the autism spectrum, with between 50% and 80% of children affected,鈥 she says.
鈥淎 combination of biological, environmental, behavioural and psychological factors contribute towards sleep problems. From a biological perspective, the timing and amount of melatonin produced in children on the spectrum can differ from typically developing children.
鈥淪leep deprivation impacts significantly on these children and their families, coming in on top of other challenges, so we feel it is important to understand how to better support them to get a good night鈥檚 sleep.鈥澨
Melatonin has been funded by Pharmac since 2017 for children on the autism spectrum who have persistent, pervasive sleep problems. It has no known significant side effects, making it an attractive option for parents. It is effective and easy to administer compared to many other treatments.听
鈥淎n effective alternative is behavioural interventions, however these require a lot of effort and time on the part of parents, as well as professional support that is not always available,鈥 Dr McLay says. 听
An expert on behavioural interventions for sleep problems, Dr McLay worked with children on the autism spectrum and their families before joining UC as a lecturer and researcher. She wanted to understand how popular melatonin was in Aotearoa New Zealand, and worked with a team of researchers including UC鈥檚 Professor Philip Schluter and doctoral student Emma Woodford, Dr Matt Eggleston from the Mental Health Division of the mini传媒 District Health Board, and Nick Bowden from the University of Otago鈥檚 Department of Women鈥檚 and Children鈥檚 Health and A Better Start National Science Challenge.
The team obtained data for 11,202 children on the autism spectrum aged up to 18 years in Aotearoa New Zealand. While the efficacy of melatonin for sleep problems in children on the autism spectrum is well-known, the rate and patterns of melatonin use in New Zealand was not.
The study, published in听Sleep Medicine听in March 2021, found that rates of melatonin dispensing were higher among females, school-aged children and those of European ethnicity. Rates were also higher among those with co-occurring mental health conditions, particularly ADHD. No difference was found in rates of melatonin dispensing for different levels of deprivation and urban/rural locations.
Dr McLay is anticipating a second study will be published later this year, looking at the secondary benefits of improving children鈥檚 sleep. 听Further research is planned to explore how melatonin could be used alongside behavioural interventions to further improve sleep for children on the autism spectrum.
The research does not explore the use of melatonin among children who are not on the autism spectrum.
Dr听McLay leads the听Good Nights Programme听at UC,听an innovative research programme and cost-free nationwide clinical service that helps children with autism get a better night's sleep.
She will present on the topic of听Quality Sleep: How can we better support children with Autism?听At the upcoming听Child Well-being Research Symposium听on 8 鈥 9 April at UC.
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